anti cdk6 (Cell Signaling Technology Inc)

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Cell Signaling Technology Inc anti cdk6
Anti Cdk6, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 355 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+cdk6/CDK6+Rabbit+mAb/pm41874002-195-31-32
Average 96 stars, based on 355 article reviews

anti cdk6 - by Bioz Stars, 2026-10

96/100 stars

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Article Title: Potential oncogenic role of occult hepatitis B virus pre-S mutations: Activation of Akt/mTOR/cyclin D1 signaling drives cell cycle dysregulation and proliferation in hepatocellular carcinogenesis
Article Snippet: The antibodies employed in 128 this research included anti-mTOR (#2983, 1:1000, Cell Signaling Tech., Danvers, 129 Massachusetts, USA), anti-Phospho-mTOR (ab109268, 1:1000, Abcam, Cambridge, 130 UK), anti-Phospho-Akt (#4060, 1:1000, Cell Signaling Tech., Danvers, 131 Massachusetts, USA), anti-Akt (#4691, 1:1000, Cell Signaling Tech., Danvers, 132 Jo urn al Pr e-p roo f 7 Massachusetts, USA), anti-Phospho-p70 S6 Kinase (#9234, 1:1000, Cell Signaling 133 Tech., Danvers, Massachusetts, USA), anti- p70 S6 kinase (sc-8418, 1:500, Santa 134 Cruz Biotechnology, Dallas, Texas, USA), anti-Cyclin D1 (#2978, 1:1000, Cell 135 Signaling Tech., Danvers, Massachusetts, USA), anti-Phospho-Rb (#85116, 1:1000, 136 Cell Signaling Tech., Danvers, Massachusetts, USA), anti-CDK4 (#12790, 1:1000, 137 Cell Signaling Tech., Danvers, Massachusetts, USA), anti-CDK6 (#13331, 1:1000, 138 Cell Signaling Tech., Danvers, Massachusetts, USA), anti-HBsAg (ab9193, 1:500, 139 Abcam, Cambridge, UK), anti-GAPDH (ab8245, 1:8000, Abcam, Cambridge, UK), 140 and anti-β-Tubulin (ab6046, 1:8000, Abcam, Cambridge, UK).

Article Title: Repurposing T-type calcium channel blocker Lomerizine as a therapeutic strategy for glioblastoma.
Article Snippet: The following primary antibodies were 464 used in this study: anti-Akt (Cell Signaling; #9272), anti-pAkt (Cell Signaling; #4058), anti-β-465 actin (FUJIFILM Wako Pure Chemical Corporation; 010-27841), anti-CDK4 (Cell Signaling; 466 #12790), anti-CDK6 (Cell Signaling; #13331), anti-ERK (Cell Signaling; #4695), anti-pERK 467 (Cell Signaling; #4370), anti-SOX2 (Gene Tex; GTX101507), anti-STAT3 (Cell Signaling; 468 #12640), anti-pSTAT3 S727 (Cell Signaling; #9134), anti-pSTAT3 Y705 (Cell Signaling; #9145), 469 and anti-PARP (Cell Signaling; #9542) , anti-Cleaved PARP (Cell Signaling; #5625).

Article Title: TRIM21 knockdown suppresses ESCC progression and induces autophagy-mediated apoptosis via AKT/mTOR signaling pathway
Article Snippet: The following antibodies were used in our study: anti-TRIM21 (Cat#sc-48,430, Santa Cruz), anti-GAPDH (Cat#T0004, Affinity), anti-Cyclin D3 (Cat#sc-6283, Santa Cruz), antiCDK4 (Cat#sc-23,896, Santa Cruz), anti-CDK6 (Cat#3136, Cell Signaling Technology), anti-p16 (Cat#80772, Cell Signaling Technology), anti-Atg12 (Cat#4180, Cell Signaling Technology), anti-Beclin1 (Cat#11306–1-AP, Proteintech), anti-LC3B (ab192890, Abcam), antip62 (Cat#80294–1-RR, Proteintech), anti-cleaved PARP1 (ab32064, Abcam), anti-BCL2 (Cat#4223, Cell Signaling Technology), anti-BAX (Cat#2772, Cell Signaling Technology), anti-mTOR (Cat#28273–1-AP, Proteintech), anti-phospho-mTOR (Cat#5536, Cell Signaling Technology), anti-total AKT (Cat#9272, Cell Signaling Technology), phosphAKT (Cat#4060, Cell Signaling Technology),

Article Title: Targeting c‐Myc enhances immunotherapy efficacy in combination with Ras inhibitor in triple‐negative breast cancer
Article Snippet: The primary antibodies of anti‐c‐Myc (1:1000, #5605), anti‐CyclinD1 (1:1000, #2978), anti‐CDK4 (1:1000, #12790), anti‐CDK6 (1:1000, #13331), anti‐Rb (1:1000, #9313), anti‐p‐Rb (1:1000, #9301), and anti‐MCM2 (1:1000, #3619) were acquired from Cell Signaling Technology (CST, USA).

Article Title: Lower early-stage rectal cancer surgical approaches: therapeutic options and cancer biomarker alterations
Article Snippet: Primary antibodies included: anti-CDK2 (#18048, 1:200, Cell Signaling Technology), anti-CDK4 (#12790, 1:200, CST), anti-CDK6 (#13331, 1:100, CST), anti-PAK4 (#52694, 1:400, CST), and anti-FOXD1 (ab129324, 1:50, Abcam).

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Article Title: Active Vitamin D Insufficiency Accelerates Skeletal Aging via Oxidative Stress and p16-Mediated Senescence
Article Snippet: .. Membraneswere blockedwith 5% non-fat milk in TBST and incubated overnight at 4 °C with the following primary antibodies: anti-Nrf2 (catalog no. BS1258, lot #A12345, dilution 1:1000; Bioworld Technology, Inc., Dublin, OH, USA), anti-Sod1 (catalog no. ab13498, lot #GR345678, dilution 1:1000; Abcam, Cambridge, UK), anti-γH2AX (catalog no. ab11174, lot #GR456789, dilution 1:1000; Abcam, Cambridge, UK), anti-CDK4 (catalog no. ab108357, lot #GR567890, dilution 1:1000; Abcam, Cambridge, UK), anti-CDK6 (catalog no. 3136, lot #25, dilution 1:1000; Cell Signaling Technology, Danvers, MA, USA), anti-p16 (catalog no. ab108349, lot #GR678901, dilution 1:1000; Abcam, Cambridge, UK), anti-p21 (catalog no. sc-6246, lot #B0123, dilution 1:500; Santa Cruz Biotechnology, Dallas, TX, USA), anti-p53 (catalog no. sc-126, lot #C0345, dilution 1:500; Santa Cruz Biotechnology, Dallas, TX, USA), anti-Cyclin D1 (catalog no. ab134175, lot #GR789012, dilution 1:1000; Abcam, Cambridge, UK), anti-Bmi1 (catalog no. 05-637, lot #DAM123456, dilution 1:1000; MilliporeSigma, Burlington, MA, USA), and anti-β-actin (catalog no. AP0060, lot #B23456, dilution 1:2000; Bioworld Technology, Inc., Dublin, OH, USA). .. HRP-conjugated secondary antibodies (dilution 1:5000; Cell Signaling Technology, Danvers, MA, USA; anti-rabbit IgG HRP catalog no. 7074, lot #28; antimouse IgG HRP catalog no. 7076, lot #29) were applied for 1 hour at room temperature.

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Article Title: Targeting PCK1 to overcome CDK4/6 inhibitor resistance for breast cancer therapy.
Article Snippet: Phosphoenolpyruvate carboxykinase 1 (PCK1) is known for its role in gluconeogenesis and the regulation of PCK1 expression was shown to associate with oncogenic activity in pancreatic and colorectal cancers.. However, in different cancer types such as liver cancer, PCK1 could function as a tumor suppressor, rendering complication for targeted therapy.. In this study, we used breast cancer model to delineate its involvement in malignancy, we found PCK1 associated with oncogenic function to promotes cell proliferation, enhances colony formation, and stimulates DNA synthesis in breast cancer.

Article Title: Activating transcription factor 4-mediated upregulation of Heat Shock Protein Family A Member 4 promotes hepatocellular carcinoma progression through activation of Wnt/β-catenin/EMT signaling pathway.
Article Snippet: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, and identifying novel biomarkers for diagnosis and prognosis is critical for improving patient outcomes.. In this study, we identified 44 differentially expressed necroptosis-related genes (DE-NERGs) in HCC using the GSE121248 dataset.. Functional analyses, including GO and KEGG pathway analyses, revealed that these genes were associated with key pathways such as NF-κB signaling, apoptosis, and cancer-related pathways.

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